ConditionsPain / Connective Tissue
Pain / Connective Tissue

Ehlers-Danlos Syndrome

Gabriel recognizes EDS is genetic and cannot be cured but can be significantly supported.

Root Causes

5 identified

Supplements

11 recommended

Lab Markers

10 to test

Treatments

2 modalities

Gabriel's Approach

Gabriel recognizes EDS is genetic and cannot be cured but can be significantly supported. He focuses on collagen support through nutrition (vitamin C, lysine, proline, copper), addresses common comorbidities (POTS, mast cell activation, gut issues), uses physical therapy to strengthen supporting muscles, addresses chronic pain with multimodal approach, supports joints with prolotherapy or PRP when appropriate, treats MCAS if present, optimizes sleep, and provides comprehensive care addressing the multi-system nature of EDS. Quality of life can be dramatically improved.

Root Causes

Genetic mutations affecting collagen production (multiple types of EDS, different genes)
Hypermobile EDS (hEDS - most common, genetic cause unknown)
Classical EDS (mutations in COL5A1, COL5A2)
Vascular EDS (COL3A1 - life-threatening)
Other rare types (various collagen and enzyme mutations)

Why Conventional Fails

Standard Treatment

Pain management (NSAIDs, gabapentin, opioids for severe cases), physical therapy (often standard PT worsens hypermobility), treat comorbidities (POTS, MCAS), genetic counseling, monitor cardiovascular complications especially vascular EDS, surgery for severe joint instability or organ complications.

The Problem

Pain medications don't address root issue and have side effects, standard physical therapy often worsens hypermobility (therapists don't understand EDS), comorbidities often undiagnosed (POTS, MCAS, gut issues), nutritional support for collagen rarely addressed, dismisses as 'just being flexible' or 'growing pains,' many doctors unfamiliar with EDS, inadequate pain management leaves patients suffering, doesn't address multi-system nature comprehensively, patients often dismissed as hypochondriacs before diagnosis.

Your Complete Protocol

A comprehensive, tiered approach combining supplements, herbs, and advanced therapies

Functional MedicineChinese Herbal MedicinePeptide TherapyWhole Food Nutrition

Your Protocol for Ehlers-Danlos Syndrome

Choose the level that's right for your healing journey

Essential Protocol

Start Here
$75/mo

What's Included

  • Vitamin C 3-5g/day (critical for collagen synthesis)
  • Lysine 3000mg/day
  • Proline 1000-3000mg/day
  • Glycine 3-5g/day
  • Vitamin C — Essential for collagen synthesis and tissue strength
  • Collagen Peptides — Provides building blocks for connective tissue repair
Get Essential Protocol

Available through Fullscript

Practitioner-Grade Protocol

Most Popular

Practitioner-Grade — Not Available on Amazon

$165/mo

What's Included

  • Standard Process whole food protocol
  • Kidney Qi Pill (Jin Gui Shen Qi Wan) — Strengthens kidney essence that governs connective tissue
  • Tonify the Middle and Augment the Qi (Bu Zhong Yi Qi Tang) — Strengthens spleen qi to support tissue integrity and prevent injury
Get Practitioner Protocol

Whole food supplements by Standard Process

Complete Protocol

Best Value
$245/mo

What's Included

  • All Practitioner-Grade supplements & herbs
  • BPC-157 (tissue repair + gut healing)
  • Thymosin Alpha-1 (immune modulation)
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Standard Process + Matter peptides

Recommended Supplements

Vitamin C 3-5g/day (critical for collagen synthesis)
Lysine 3000mg/day
Proline 1000-3000mg/day
Glycine 3-5g/day
Collagen peptides 20g/day
Copper 2-3mg
Zinc 30mg
Vitamin D3 5000-10,000 IU
Magnesium Glycinate 400-600mg
Omega-3 4g/day
CoQ10 300mg (mitochondrial support)

Key Lab Markers

Genetic testing (confirm EDS type)
Echocardiogram (check for mitral valve prolapse, aortic dilation especially vascular EDS)
Vitamin C
Copper
Zinc
Vitamin D
Tryptase (mast cell activation)
Tilt table test if POTS suspected
Comprehensive stool test (gut issues common)
Sleep study (sleep apnea common)

Dietary Guidance

High vitamin C foods (citrus, berries, bell peppers, broccoli, kiwi) at every meal for collagen synthesis, adequate protein for amino acids (collagen peptides, bone broth, grass-fed meats, wild fish, eggs), avoid foods that interfere with collagen (high sugar damages collagen cross-linking), anti-inflammatory diet (many EDS patients have mast cell activation), some need low-histamine diet, adequate salt and hydration if POTS present, avoid alcohol (affects collagen quality and worsens joint laxity), bone broth daily, vitamin C-rich smoothies.

Lifestyle Factors

Physical therapy focusing on muscle strengthening to support hypermobile joints (NOT stretching - already too flexible), avoid hypermobility (learn to move within normal range), joint protection techniques, bracing for unstable joints, avoid contact sports and activities with high injury risk, pacing (avoid overexertion and crashes), pain management (multiple modalities), sleep optimization (special pillows for neck instability), compression garments if POTS, avoid extreme temperatures, careful with massage (can cause subluxations), genetic counseling if planning children.

Mind, Body & Spirit

Evidence-based practices that complement physical treatment protocols

Mind

Pain Management Counseling

strong

Coping with chronic pain, pacing, and lifestyle adaptations.

Meditation for Chronic Illness

moderate

Managing pain, anxiety, and the emotional burden of multi-system genetic condition.

Body

EDS-Specific Physical Therapy

strong

Specialized PT focusing on strengthening, not stretching, joint protection techniques.

Prolotherapy / PRP

moderate

Injection therapy to stabilize chronically loose joints.

Gentle Yoga (Modified)

moderate

Careful practice avoiding hypermobility, focusing on stability and body awareness.

Occupational Therapy

strong

Adaptive equipment, joint protection, ergonomic modifications for daily activities.

Spirit

Support Groups

moderate

Connection with EDS community reduces isolation and provides practical management tips.

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