Inflammation / Immune
Complement C4
Unit: mg/dLID: I008
What This Test Measures
Immune system protein; part of complement cascade
Conventional vs. Functional Optimal Range
Conventional "Normal"
10-40 mg/dLYour doctor says you're "fine" anywhere in this range
Functional Optimal
15-35 mg/dLThis is where you actually feel great
The gap between these ranges is why you feel terrible with "normal" labs. Conventional medicine waits for disease. Functional medicine optimizes for health.
Gabriel's Take
C4 parallels C3. Low C3 + low C4 = autoimmune disease (lupus, vasculitis). Low C4 alone = hereditary angioedema. Should be mid-range (15-35). Functional medicine checks complement in autoimmune workups.
When This Test Is High
Inflammation, infection
When This Test Is Low
Autoimmune disease (consumption), genetic deficiency
Related Conditions
Lupus, immune complex disease
Recommended Follow-Up
Check with C3; if both low, suggests autoimmune disease or consumption
Related Tests in Inflammation / Immune
C-Reactive Protein (CRP) / hs-CRP
Inflammatory marker; predictor of cardiovascular disease
View details→
hs-CRP (High-Sensitivity C-Reactive Protein)
Sensitive inflammatory marker; cardiovascular risk predictor
View details→
ESR (Erythrocyte Sedimentation Rate)
Non-specific inflammation marker
View details→