Inflammation / Immune

Complement C4

Unit: mg/dLID: I008

What This Test Measures

Immune system protein; part of complement cascade

Conventional vs. Functional Optimal Range

Conventional "Normal"
10-40 mg/dL
Your doctor says you're "fine" anywhere in this range
Functional Optimal
15-35 mg/dL
This is where you actually feel great

The gap between these ranges is why you feel terrible with "normal" labs. Conventional medicine waits for disease. Functional medicine optimizes for health.

Gabriel's Take

C4 parallels C3. Low C3 + low C4 = autoimmune disease (lupus, vasculitis). Low C4 alone = hereditary angioedema. Should be mid-range (15-35). Functional medicine checks complement in autoimmune workups.

When This Test Is High

Inflammation, infection

When This Test Is Low

Autoimmune disease (consumption), genetic deficiency

Related Conditions

Lupus, immune complex disease

Recommended Follow-Up

Check with C3; if both low, suggests autoimmune disease or consumption