DHEA-S
What This Test Measures
Adrenal androgen precursor; resilience and vitality
Conventional vs. Functional Optimal Range
The gap between these ranges is why you feel terrible with "normal" labs. Conventional medicine waits for disease. Functional medicine optimizes for health.
Gabriel's Take
DHEA-S declines with age and chronic stress, so compare it with your age range. Gabriel's optimal band: 300-416 for men, 150-279 for women, aiming for the upper half of your age range when older. Trials of DHEA supplements in older adults did not improve body composition, performance or quality of life (NEJM, 2006), and DHEA can cause acne and unwanted hair growth in women, so it isn't a way to chase a number. High in women = PCOS or adrenal tumor.
When This Test Is High
Adrenal tumor, PCOS
When This Test Is Low
Adrenal fatigue, aging, chronic stress
Related Conditions
Adrenal dysfunction, low vitality, immune suppression
Recommended Follow-Up
If low, address stress and sleep; DHEA supplements are a clinician's decision; if high (women), rule out PCOS