Hormones
SHBG (Sex Hormone Binding Globulin)
Unit: nmol/LID: H008
What This Test Measures
Protein that binds sex hormones; regulates free hormone levels
Conventional vs. Functional Optimal Range
Conventional "Normal"
10-80 nmol/LYour doctor says you're "fine" anywhere in this range
Functional Optimal
30-46 (men), 50-80 (women) nmol/LThis is where you actually feel great
The gap between these ranges is why you feel terrible with "normal" labs. Conventional medicine waits for disease. Functional medicine optimizes for health.
Gabriel's Take
SHBG binds testosterone and estrogen, reducing free (active) levels. Low SHBG = insulin resistance, PCOS. High SHBG = low free testosterone despite normal total T. Gabriel's optimal band: 30-46 for men, 50-80 for women. SHBG is the key to interpreting Total vs Free testosterone.
When This Test Is High
Hyperthyroidism, estrogen excess, low androgens
When This Test Is Low
Hypothyroidism, insulin resistance, PCOS
Related Conditions
High SHBG: low free testosterone; Low SHBG: insulin resistance, PCOS
Recommended Follow-Up
Check Free Testosterone; if SHBG low, address insulin resistance; if high, check thyroid