Thyroid-Supporting
Ashwagandha
Directly increases T4 and T3 levels in subclinical hypothyroidism. Reduces cortisol (high cortisol suppresses thyroid). Adaptogenic support for HPA-thyroid axis.
Caution: Ashwagandha
70+ case reports of liver injury. Risk higher with leaf-based extracts, adulterated products, concurrent hepatotoxic medications, or pre-existing liver conditions. Root-only extracts from reputable sources (KSM-66, Sensoril) show strong safety in clinical trials (191 participants, 12 months, no liver effects).
Safe Use Guidance:
Use root-only extracts from reputable brands (KSM-66, Sensoril). Limit initial course to 3 months. Monitor liver enzymes if risk factors present. Avoid if pre-existing liver disease or concurrent hepatotoxic medications.
Sources:
Mechanism of Action
Directly increases T4 and T3 levels in subclinical hypothyroidism. Reduces cortisol (high cortisol suppresses thyroid). Adaptogenic support for HPA-thyroid axis.
Active Compounds
Therapeutic Applications
Serving Size & Preparation
Recommended Serving Size
300-600mg extract daily
Preparation Guidelines
Standardized extract (withanolide content). KSM-66 or Sensoril brands. Take with meals. Effects in 4-8 weeks
Synergistic Combinations
These foods and compounds enhance the therapeutic effects of Ashwagandha:
Additional Notes
One of few herbs shown to increase thyroid hormones directly
Safety Information
Contraindications
Hyperthyroidism, pregnancy, autoimmune thyroid (may overstimulate), nightshade sensitivity
Quick Facts
Evidence Level
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