ConditionsNeurological / Pain
Neurological / Pain

Small Fiber Neuropathy

Gabriel investigates root cause through comprehensive testing: glucose tolerance test and HbA1c (catch prediabetes), vitamin levels, autoimmune markers, Lyme testing, genetic testing, heavy metals.

Root Causes

10 identified

Supplements

11 recommended

Lab Markers

14 to test

Treatments

6 modalities

Gabriel's Approach

Gabriel investigates root cause through comprehensive testing: glucose tolerance test and HbA1c (catch prediabetes), vitamin levels, autoimmune markers, Lyme testing, genetic testing, heavy metals. He uses high-dose B vitamins for nerve repair, alpha-lipoic acid (proven for diabetic neuropathy), addresses blood sugar and insulin resistance, treats infections, supports mitochondrial function, uses anti-inflammatory protocols, and combines supplements with physical therapy, acupuncture, and pain management. Early intervention prevents permanent damage.

Root Causes

Diabetes and prediabetes (most common - high blood sugar damages small nerves)
Autoimmune conditions (Sjogren's, lupus, celiac disease)
Vitamin deficiencies (B12, B1, B6, folate)
Toxin exposure (alcohol, chemotherapy, heavy metals)
Infections (Lyme disease, hepatitis C, HIV)
Genetic disorders (Fabry disease, hereditary sensory neuropathy)
Medications (statins, fluoroquinolones, chemotherapy)
MTHFR and methylation issues
Mitochondrial dysfunction
Idiopathic (no cause found in 50%)

Why Conventional Fails

Standard Treatment

Pain medications (gabapentin, pregabalin, duloxetine, tricyclic antidepressants), topical treatments (lidocaine, capsaicin), treat underlying cause if identified (blood sugar control, B12 supplementation), sometimes opioids for severe pain, physical therapy.

The Problem

Focuses on pain management without aggressive root cause treatment, medications have significant side effects (sedation, weight gain, cognitive impairment), doesn't use alpha-lipoic acid (proven effective but rarely prescribed), misses prediabetes (only tests fasting glucose, not OGTT or insulin), doesn't optimize B vitamins adequately, doesn't test for Lyme or autoimmune causes comprehensively, doesn't support mitochondrial function or nerve regeneration, many cases labeled 'idiopathic' without thorough investigation.

Your Complete Protocol

A comprehensive, tiered approach combining supplements, herbs, and advanced therapies

Functional MedicineChinese Herbal MedicinePeptide TherapyWhole Food Nutrition

Your Protocol for Small Fiber Neuropathy

Choose the level that's right for your healing journey

Essential Protocol

Start Here
$75/mo

What's Included

  • Alpha-Lipoic Acid 600mg 3x/day (proven for neuropathy)
  • Methylcobalamin B12 5000-10,000mcg
  • Benfotiamine (fat-soluble B1) 300mg 2x/day
  • Methylfolate 5mg
  • Alpha Lipoic Acid — Powerful antioxidant that helps repair small nerve fibers
  • B-Complex Vitamins — Essential for nerve health and repair
Get Essential Protocol

Available through Fullscript

Practitioner-Grade Protocol

Most Popular

Practitioner-Grade — Not Available on Amazon

$165/mo

What's Included

  • Standard Process whole food protocol
  • Four Substance Decoction (Si Wu Tang) — Nourishes blood to feed and repair damaged small nerve fibers
  • Rehmannia Six Formula (Liu Wei Di Huang Wan) — Nourishes kidney yin to clear heat and support nerve health
Get Practitioner Protocol

Whole food supplements by Standard Process

Complete Protocol

Best Value
$245/mo

What's Included

  • All Practitioner-Grade supplements & herbs
  • BPC-157 (tissue repair + gut healing)
  • Thymosin Alpha-1 (immune modulation)
Get Complete Protocol

Standard Process + Matter peptides

Recommended Supplements

Alpha-Lipoic Acid 600mg 3x/day (proven for neuropathy)
Methylcobalamin B12 5000-10,000mcg
Benfotiamine (fat-soluble B1) 300mg 2x/day
Methylfolate 5mg
B6 as P5P 50-100mg
Acetyl-L-Carnitine 2000mg/day
Omega-3 4g/day
Curcumin 2000mg 2x/day
Magnesium Glycinate 400-600mg
CoQ10 300mg
NAC 1200mg 2x/day

Key Lab Markers

Skin biopsy with IENFD (intraepidermal nerve fiber density - diagnostic for SFN)
Oral glucose tolerance test with insulin (catch prediabetes)
HbA1c
Fasting insulin
B12, MMA, homocysteine
B1 (thiamine)
B6
Folate
ANA, SSA/SSB (Sjogren's)
Celiac panel
Lyme testing
Heavy metals
Genetic testing (MTHFR, SCN9A)
TSH

Dietary Guidance

Low-glycemic anti-inflammatory diet critical (even if not diabetic, blood sugar control protects nerves), eliminate refined sugars and carbohydrates, adequate B vitamins from food (grass-fed meats, wild fish, eggs, leafy greens), omega-3 rich foods, antioxidant-rich colorful vegetables and berries, alpha-lipoic acid from red meat and organ meats, avoid alcohol completely (toxic to nerves), eliminate gluten if celiac or sensitivity, avoid high omega-6 vegetable oils (pro-inflammatory), adequate protein for nerve repair, healthy fats for myelin.

Lifestyle Factors

Tight blood sugar control if diabetic or prediabetic (prevents progression), protect affected areas (inspect feet daily, proper footwear, avoid injury), manage pain (acupuncture, TENS unit, capsaicin cream, lidocaine patches), physical therapy and balance training (prevent falls from numbness), stress management (stress affects pain perception), adequate sleep (nerve repair during sleep), avoid smoking and alcohol (worsen neuropathy), treat depression common with chronic pain, address medication side effects, cold therapy or warm therapy depending on what helps individual.

Mind, Body & Spirit

Evidence-based practices that complement physical treatment protocols

Mind

Meditation for Chronic Pain

strong

Mindfulness-based pain reduction to manage burning, tingling, allodynia.

Cognitive Behavioral Therapy

strong

Coping strategies for chronic pain and lifestyle limitations.

Graded Motor Imagery

moderate

Brain retraining for allodynia and pain hypersensitivity.

Body

Acupuncture for Neuropathy

strong

Acupuncture proven effective for neuropathic pain and nerve function.

TENS Unit

moderate

Transcutaneous electrical nerve stimulation for pain relief.

Physical Therapy

strong

Balance and gait training, desensitization techniques, fall prevention.

Spirit

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