Secretory IgA (sIgA)
What This Test Measures
First-line gut immune defense; mucosal immunity
Conventional vs. Functional Optimal Range
The gap between these ranges is why you feel terrible with "normal" labs. Conventional medicine waits for disease. Functional medicine optimizes for health.
Gabriel's Take
Secretory IgA is the gut's immune defense. Low sIgA (<500) = weakened gut immunity → infections, leaky gut, dysbiosis. Often low in chronic stress ("adrenal fatigue"). High sIgA (>2000) = acute gut infection. Functional optimal 800-1800. Integrative practitioners support sIgA with stress management, probiotics and colostrum.
When This Test Is High
Acute gut infection, inflammation
When This Test Is Low
Chronic stress, adrenal fatigue, immune suppression
Related Conditions
Low: leaky gut, infections, adrenal fatigue; High: acute gut infection
Recommended Follow-Up
If low, support adrenals, reduce stress, probiotics; if high, rule out infection