Cathelicidin
Also known as: LL-37, hCAP-18, CAMP
Human antimicrobial peptide with broad-spectrum activity and immunomodulatory properties.
Benefits
6
Conditions
6
Evidence
Extensive in vitro research, preclinical models, limited human trials+ studies
Source
Human endogenous cathelicidin peptide, synthesized or recombinant
Gabriel Brain Score
Moderate
Overview
Human antimicrobial peptide with broad-spectrum activity and immunomodulatory properties.
Mechanism of Action
Disrupts bacterial, fungal, and viral membranes, neutralizes LPS endotoxins, inhibits biofilm formation, chemotactic for immune cells, promotes wound healing and angiogenesis, modulates inflammatory response.
Key Benefits
- ✓Broad-spectrum antimicrobial activity
- ✓Anti-biofilm effects
- ✓Immunomodulation
- ✓Wound healing promotion
- ✓Antiviral properties
- ✓Endotoxin neutralization
Clinical Applications
Dosing Guidelines
Topical
Subcutaneous injection (research)
* Dosing should be individualized. Always consult with a qualified healthcare practitioner.
Research & Evidence
Extensive in vitro research, preclinical models, limited human trials
Well-characterized antimicrobial and immunomodulatory mechanisms. Deficiency linked to skin conditions like rosacea. Clinical trials limited but promising for wound care and infection control.
Safety Information
Potential Side Effects
- •Local irritation (topical)
- •Potential cytotoxicity at high doses
Contraindications
- Under investigation
Interactions
- ⚠Unknown
Quick Facts
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