Fasting Mimicking Diet (FMD)
5-day low-calorie, low-protein, plant-based diet (800-1100 cal/day) that mimics fasting metabolically while providing some nutrition.
86/100
Valter Longo
5-day cycles monthly or quarterly
11 phases
4 targeted
Protocol Overview
5-day low-calorie, low-protein, plant-based diet (800-1100 cal/day) that mimics fasting metabolically while providing some nutrition. Triggers autophagy and stem cell regeneration without full fast. ProLon is commercial product.
Conditions Treated
Key Resources
Safety Profile
Gold-standard research from Valter Longo at USC. Clinical trials show immune regeneration, stem cell activation, metabolic benefits. Safer than water fasting (less extreme). ProLon is convenient but expensive. Can DIY with same macro targets. Used in cancer clinics as adjunct to chemo. Strong science. Most evidence-based fasting protocol. Accessible compromise between normal eating and extended fasting.
About Evidence Score
The Evidence Score rates the strength of clinical and scientific evidence behind this protocol. Higher scores indicate stronger research support. This is a research tool, not medical advice.
Educational purposes only. Some alternative protocols carry serious risks. Always consult qualified healthcare professionals before beginning any treatment.