gutHigh

Fecal Microbiota Transplant (FMT)

Transfer of screened donor stool to restore a healthy gut microbiome, done by a clinician.

Evidence Score

90/100

Developer

Various (clinical researchers)

Duration

Single treatment or a short series, as your clinician decides

Steps

7 phases

Used for

2 conditions

Protocol Overview

Transfer of screened donor stool to restore a healthy gut microbiome, done by a clinician. Two FDA-approved fecal microbiota products are used to prevent recurrent C. diff infection in adults after antibiotic treatment: a rectal product approved in November 2022 and oral capsules approved in April 2023. Other uses are experimental.

Used For

Recurrent C. difficile infectionUlcerative colitis (under study)

Key Resources

FDA safety communications on FMT
Clinical trials (clinicaltrials.gov)

Safety Profile

Contraindications & Risks
Immunocompromised people need specialist review (higher infection risk), severe active colitis, home or unscreened FMT (can transmit serious infections)
Important Notes

In trials, FMT stops C. diff from coming back in most people with recurrent infection. Results for ulcerative colitis are promising but modest, and evidence for IBS and other conditions is mixed. In 2019 the FDA reported serious drug-resistant infections, including one death, from donor stool that had not been screened for those bacteria.

Find a Practitioner

Gabriel can find and book a practitioner who works with this approach.

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EvidenceHigh
Evidence Score90/100
Categorygut
DurationSingle treatment or a short series, as your clinician decides

About Evidence Score

The Evidence Score (0 to 100) rates the strength of evidence from studies in people for the uses listed: higher means stronger, more consistent research. It does not measure safety. It is not medical advice.

For education, not medical advice. Talk with a licensed clinician before you start, and never stop or change a prescribed medication without your prescriber.