Brain/Cognitive
Sage
Inhibits acetylcholinesterase (increases acetylcholine). Anti-inflammatory effects on brain. Improves attention and memory in healthy adults and Alzheimer's patients.
Mechanism of Action
Inhibits acetylcholinesterase (increases acetylcholine). Anti-inflammatory effects on brain. Improves attention and memory in healthy adults and Alzheimer's patients.
Active Compounds
Therapeutic Applications
Serving Size & Preparation
Recommended Serving Size
1-2 tsp fresh or tea daily
Preparation Guidelines
Fresh herb in cooking, tea, or tincture. Common sage (S. officinalis) most studied
Synergistic Combinations
These foods and compounds enhance the therapeutic effects of Sage:
Additional Notes
Used traditionally for memory - modern science confirms
Safety Information
Contraindications
Pregnancy (high doses), seizure disorders (thujone in very high doses)
Quick Facts
Evidence Level
Related Foods
Wild Salmon/Sardines (Brain)
DHA is primary structural fat in brain (97% of omega-3s in brain). Supports neuronal membrane fluidity, neurotransmitter production. EPA reduces neuroinflammation. Astaxanthin crosses BBB (antioxidant).
Blueberries (Brain)
Anthocyanins cross BBB and accumulate in hippocampus (memory). Increase BDNF (brain-derived neurotrophic factor). Improve neuronal signaling. Reduce oxidative stress and neuroinflammation.
Eggs (Pastured)
Choline precursor to acetylcholine (memory neurotransmitter). Lutein and zeaxanthin accumulate in brain (processing speed). DHA in yolks. B12 prevents brain atrophy.