Feverfew
Tanacetum parthenium
Tradition of Use: Western, European traditional
Mechanism of Action
Inhibits prostaglandin synthesis, serotonin release, platelet aggregation, anti-inflammatory
Key Conditions & Uses
Preparation
Capsule, tincture, fresh leaf
Dosage
50-150mg dried leaf (0.2% parthenolide) daily or 1-2 fresh leaves
Active Compounds
Parthenolide, sesquiterpene lactones, flavonoids
Interactions
May interact with anticoagulants, NSAIDs; can cause rebound headaches if stopped abruptly
Contraindications
Pregnancy; breastfeeding; ragweed allergy; surgery; anticoagulant use
Evidence Level & Clinical Notes
Evidence Level:
Good - effective for migraine prevention
Clinical Notes:
Preventive, not acute treatment; takes 4-6 weeks; fresh leaf can cause mouth ulcers; don't stop abruptly
Traditional Chinese Medicine Context
Xiao Bai Ju
Prevents migraines by reducing inflammation in blood vessels
Conditions This Helps
Used In These Protocols
Quick Overview
Key Points
This information is for educational purposes. Always consult with a qualified healthcare provider before starting any herbal protocol or supplement regimen.
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