Goldenseal
Hydrastis canadensis
Tradition of Use: Western, Native American
Mechanism of Action
Berberine inhibits bacterial adhesion, anti-inflammatory via NF-κB pathway, antimicrobial
Key Conditions & Uses
Preparation
Tincture, capsule, tea, eye wash
Dosage
250-500mg 3x daily or 2-4ml tincture 3x daily
Active Compounds
Berberine, hydrastine, canadine
Interactions
Potentiates anticoagulants; interferes with CYP450 enzymes; enhances metformin
Contraindications
Pregnancy; breastfeeding; hypertension; long-term use
Evidence Level & Clinical Notes
Evidence Level:
Moderate - berberine well-studied
Clinical Notes:
Overharvested and endangered; berberine is main active compound
Conditions This Helps
Quick Overview
Key Points
This information is for educational purposes. Always consult with a qualified healthcare provider before starting any herbal protocol or supplement regimen.
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