Rainforest/Indigenous

Guarana

Paullinia cupana

Tradition of Use: Amazonian indigenous, Western adoption

Mechanism of Action

Stimulant (high caffeine), thermogenic, cognitive enhancement, appetite suppressant, antioxidant

Key Conditions & Uses

Fatigue

weight loss

cognitive function

athletic performance

headache

Preparation

Capsule, powder, drink

Dosage

50-200mg (providing 25-75mg caffeine) 1-2x daily

Active Compounds

Caffeine (2x coffee), tannins, saponins, catechins

Interactions

May interact with stimulants, MAO inhibitors, anticoagulants, lithium

Contraindications

Pregnancy; anxiety; cardiovascular disease; insomnia; high blood pressure

Evidence Level & Clinical Notes

Evidence Level:

Moderate - caffeine content and cognitive effects documented

Clinical Notes:

Seeds used; highest natural caffeine (guaranine); sustained energy release; traditional Amazonian; antioxidant

Conditions This Helps

Chronic Fatigue / Fibromyalgia Obesity / Weight Loss Resistance Temporal Arteritis (Giant Cell Arteritis)

Quick Overview

TraditionRainforest/Indigenous

GBS Score73/100

Key Uses5

Key Points

Evidence-based information

Traditional wisdom

Safety information

Clinical applications

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