BPC-157
Also known as: Body Protection Compound-157, Pentadecapeptide BPC-157
Synthetic pentadecapeptide derived from gastric protein BPC with potent tissue regeneration and healing properties.
Benefits
6
Conditions
7
Evidence
Multiple preclinical rat studies, emerging human case reports+ studies
Source
Synthetic derivative of gastric protective protein
Gabriel Brain Score
Moderate
Overview
Synthetic pentadecapeptide derived from gastric protein BPC with potent tissue regeneration and healing properties.
Mechanism of Action
Activates FAK-paxillin and VEGFR2 pathways for angiogenesis, upregulates growth hormone receptors and JAK-2 for tissue regeneration, modulates nitric oxide (Akt-eNOS pathway) for vascular dilation, downregulates Nos2 and Nfkb inflammatory genes.
Key Benefits
- ✓Accelerates healing of tendons, ligaments, muscles, and gut tissue
- ✓Enhances angiogenesis and blood vessel formation
- ✓Promotes collagen production and tissue remodeling
- ✓Reduces inflammation without suppressing immune response
- ✓Neuroprotective effects on brain tissue
- ✓Supports gut repair and intestinal healing
Clinical Applications
Dosing Guidelines
Subcutaneous injection
Oral
* Dosing should be individualized. Always consult with a qualified healthcare practitioner.
Research & Evidence
Multiple preclinical rat studies, emerging human case reports
Strong preclinical evidence in animal models for tissue repair and angiogenesis. Human clinical trials are limited but emerging data supports efficacy for orthopedic and gastrointestinal applications.
Safety Information
Potential Side Effects
- •Injection site reactions
- •Nausea (oral)
- •Fatigue
- •Headache
Contraindications
- Active cancer (theoretical concern)
- Pregnancy
- Breastfeeding
Interactions
- ⚠May interact with anticoagulants due to angiogenic effects