Growth HormoneModerate Evidence

CJC-1295 with DAC

Also known as: CJC-1295 DAC, Drug Affinity Complex CJC

Extended-release GHRH analog with drug affinity complex providing week-long GH elevation.

Benefits

6

Conditions

5

Evidence

Clinical trials, pharmacokinetic studies+ studies

Source

Synthetic GHRH analog with drug affinity complex

Overview

Extended-release GHRH analog with drug affinity complex providing week-long GH elevation.

Mechanism of Action

GHRH analog with DAC modification binding to albumin for extended half-life (6-8 days), provides sustained GH and IGF-1 elevation, mimics continuous GHRH stimulation rather than pulsatile.

Key Benefits

  • Long-lasting GH elevation (one injection per week)
  • Sustained IGF-1 increase
  • Convenience of infrequent dosing
  • Muscle growth support
  • Improved recovery
  • Body composition benefits

Clinical Applications

Growth hormone deficiencyAge-related GH declineMuscle wastingBody composition goalsRecovery optimization

Dosing Guidelines

Subcutaneous injection

Typical Dose2 mg
FrequencyOnce or twice weekly
Duration8-12 weeks

* Dosing should be individualized. Always consult with a qualified healthcare practitioner.

Research & Evidence

Evidence Level
Moderate
Studies

Clinical trials, pharmacokinetic studies

Summary

Clinical evidence for sustained GH and IGF-1 elevation. Provides continuous rather than pulsatile GH release, which may be less physiologic than modified GRF (CJC-1295 no DAC).

Safety Information

Potential Side Effects

  • Water retention
  • Increased hunger
  • Numbness/tingling
  • Headache
  • Fatigue

Contraindications

  • Active cancer
  • Diabetic retinopathy
  • Pregnancy
  • Breastfeeding

Interactions

  • May affect glucose metabolism

Quick Facts

CategoryGrowth Hormone
SourceSynthetic GHRH analog with drug affinity complex
Legal StatusResearch compound, not FDA approved
Gabriel Brain Score
80/ 100

Source Your Protocol

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