CosmeticModerate Evidence

Collagen Peptides

Also known as: Hydrolyzed collagen, Collagen hydrolysate, Bioactive collagen peptides

Hydrolyzed collagen fragments that support skin, joint, and connective tissue health through oral supplementation.

Benefits

6

Conditions

6

Evidence

Multiple RCTs for skin and joint health+ studies

Source

Hydrolyzed from bovine, porcine, marine, or chicken collagen

Overview

Hydrolyzed collagen fragments that support skin, joint, and connective tissue health through oral supplementation.

Mechanism of Action

Dipeptides and tripeptides from collagen hydrolysis absorbed intact in GI tract, specific sequences (Gly-Pro-Hyp) signal fibroblasts to increase collagen synthesis, supports cartilage matrix production, provides amino acids for tissue repair.

Key Benefits

  • Improves skin hydration and elasticity
  • Reduces wrinkles and fine lines
  • Supports joint health
  • Strengthens hair and nails
  • Promotes wound healing
  • Supports gut barrier function

Clinical Applications

Skin agingOsteoarthritisJoint painWeak nails and hairWound healingLeaky gut

Dosing Guidelines

Oral powder or capsules

Typical Dose5-15 grams
FrequencyOnce daily
DurationOngoing for maintenance, benefits visible after 4-8 weeks

* Dosing should be individualized. Always consult with a qualified healthcare practitioner.

Research & Evidence

Evidence Level
Moderate
Studies

Multiple RCTs for skin and joint health

Summary

Clinical trials show improvements in skin elasticity, hydration, and wrinkle depth. Evidence for joint pain reduction in osteoarthritis. Well-tolerated with strong safety profile. Popular evidence-based supplement.

Safety Information

Potential Side Effects

  • Minimal
  • Mild GI upset
  • Fullness

Contraindications

  • Allergy to source (bovine, marine, etc.)

Interactions

  • None significant

Quick Facts

CategoryCosmetic
SourceHydrolyzed from bovine, porcine, marine, or chicken collagen
Legal StatusDietary supplement, GRAS status
Gabriel Brain Score
76/ 100

Source Your Protocol

Our preferred peptide partner offers lab-tested, COA-verified peptides with optional physician oversight. Sourced from US-regulated facilities.