Palmitoyl Tripeptide
Also known as: Pal-GHK, Biopeptide-CL
Palmitoylated tripeptide that enhances skin penetration and stimulates collagen synthesis for anti-aging.
Benefits
6
Conditions
5
Evidence
Cosmetic clinical trials, in vitro studies+ studies
Source
Synthetic palmitoylated tripeptide
Gabriel Brain Score
Moderate
Overview
Palmitoylated tripeptide that enhances skin penetration and stimulates collagen synthesis for anti-aging.
Mechanism of Action
Palmitic acid attachment enhances lipid membrane penetration, signals fibroblasts to increase collagen I and III production, stimulates glycosaminoglycan synthesis, promotes tissue remodeling and repair.
Key Benefits
- ✓Enhanced collagen production
- ✓Improved skin firmness
- ✓Wrinkle reduction
- ✓Better skin texture
- ✓Increased dermal thickness
- ✓Enhanced penetration vs non-palmitoylated peptides
Clinical Applications
Dosing Guidelines
Topical serum/cream
* Dosing should be individualized. Always consult with a qualified healthcare practitioner.
Research & Evidence
Cosmetic clinical trials, in vitro studies
Clinical trials show improvements in wrinkle depth and skin elasticity. Well-studied cosmetic ingredient. Palmitoylation enhances efficacy vs non-modified peptides.
Safety Information
Potential Side Effects
- •Minimal
- •Rare skin irritation
Contraindications
- Allergy to ingredients
Interactions
- ⚠Synergistic with retinoids and vitamin C
Quick Facts
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Snap-8
Extended version of Argireline with enhanced potency (~30% more effective) for wrinkle reduction.