NeuroprotectivePreclinical Evidence

Dihexa

Also known as: N-hexanoic-Tyr-Ile-(6) aminohexanoic amide

Potent cognitive enhancer that activates hepatocyte growth factor (HGF) pathway for synaptic plasticity.

Benefits

6

Conditions

6

Evidence

Preclinical animal studies, in vitro research+ studies

Source

Synthetic HGF/c-Met pathway modulator

Overview

Potent cognitive enhancer that activates hepatocyte growth factor (HGF) pathway for synaptic plasticity.

Mechanism of Action

Activates HGF/c-Met receptor pathway (7x more potent than BDNF), promotes synaptogenesis and dendritic spine formation, enhances learning and memory consolidation, supports neuronal repair and regeneration.

Key Benefits

  • ✓Powerful cognitive enhancement
  • ✓Improves memory formation and recall
  • ✓Promotes synaptic plasticity
  • ✓Supports recovery from cognitive decline
  • ✓Neuroprotective effects
  • ✓Enhances learning capacity

Clinical Applications

Alzheimer's diseaseAge-related cognitive declineMemory impairmentTraumatic brain injuryLearning disabilitiesCognitive deficits

Dosing Guidelines

Subcutaneous injection

Typical Dose0.5-2 mg
FrequencyOnce daily
DurationResearch protocols vary

Intranasal

Typical Dose1-5 mg
FrequencyOnce daily
DurationResearch protocols vary

* Dosing should be individualized. Always consult with a qualified healthcare practitioner.

Research & Evidence

Evidence Level
Preclinical
Studies

Preclinical animal studies, in vitro research

Summary

Strong preclinical evidence for cognitive enhancement and synaptogenesis. No human clinical trials published. Potent effects in animal models of Alzheimer's and cognitive impairment.

Safety Information

Potential Side Effects

  • •Unknown in humans
  • •Potential overstimulation
  • •Sleep disturbances

Contraindications

  • Pregnancy
  • Breastfeeding
  • Children

Interactions

  • ⚠Unknown - no human data

Quick Facts

CategoryNeuroprotective
SourceSynthetic HGF/c-Met pathway modulator
Legal StatusResearch compound, not approved for human use
Gabriel Brain Score
90/ 100

Source Your Protocol

Our preferred peptide partner offers lab-tested, COA-verified peptides with optional physician oversight. Sourced from US-regulated facilities.

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