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Also known as: FST, FS-344
Myostatin inhibitor that promotes dramatic muscle hypertrophy and strength gains.
Benefits
5
Conditions
5
Evidence
Preclinical animal studies, limited human data+ studies
Source
Recombinant human follistatin
Gabriel Brain Score
Moderate
Myostatin inhibitor that promotes dramatic muscle hypertrophy and strength gains.
Inhibits myostatin (muscle growth limiter), activates IGF-1R/Akt/mTOR pathway for protein synthesis, promotes Smad1/5 signaling, induces muscle hypertrophy even in low-IGF-1 states, increases IGFBP-5.
* Dosing should be individualized. Always consult with a qualified healthcare practitioner.
Preclinical animal studies, limited human data
Strong preclinical evidence for muscle growth in animal models. Human data limited to bodybuilding community reports. Mechanisms well-characterized but human clinical trials lacking.
Synthetic GHRH analog FDA-approved for reducing visceral adipose tissue in HIV-associated lipodystrophy.
Potent hexapeptide ghrelin mimetic with strong GH-releasing effects and cardioprotective properties.
Long-acting GHRH analog that stimulates sustained growth hormone release.