Growth HormoneModerate Evidence

Hexarelin

Also known as: Examorelin

Potent hexapeptide ghrelin mimetic with strong GH-releasing effects and cardioprotective properties.

Benefits

Conditions

Evidence

Clinical trials, preclinical cardioprotection research+ studies

Source

Synthetic hexapeptide ghrelin mimetic

Gabriel Brain Score

Moderate

Overview

Potent hexapeptide ghrelin mimetic with strong GH-releasing effects and cardioprotective properties.

Mechanism of Action

Binds GHS-R1a ghrelin receptor with high affinity, produces large GH pulses (greater than GHRP-6), also binds CD36 receptor for cardioprotection independent of GH, may desensitize with chronic use.

Key Benefits

✓Very potent GH release
✓Cardioprotective effects
✓Increased muscle mass
✓Enhanced recovery
✓Improved bone density
✓Neuroprotection

Clinical Applications

Growth hormone deficiencyMuscle wastingCardiac dysfunction (investigational)Age-related GH declineOsteoporosis

Dosing Guidelines

Subcutaneous injection

Typical Dose100-200 mcg

Frequency1-2 times daily

DurationCycles of 4-8 weeks (desensitization concern)

* Dosing should be individualized. Always consult with a qualified healthcare practitioner.

Research & Evidence

Evidence Level

Moderate

Studies

Clinical trials, preclinical cardioprotection research

Summary

Clinical trials demonstrate potent GH release. Unique cardioprotective effects via CD36 shown in preclinical models. Desensitization limits long-term continuous use.

Safety Information

Potential Side Effects

•Increased hunger
•Water retention
•Cortisol elevation (mild)
•Desensitization with prolonged use

Contraindications

Active cancer
Pregnancy
Breastfeeding

Interactions

⚠Synergistic with GHRH analogs

Quick Facts

CategoryGrowth Hormone

SourceSynthetic hexapeptide ghrelin mimetic

Legal StatusResearch compound, not FDA approved

Gabriel Brain Score

83/ 100

Source Your Protocol

Our preferred peptide partner offers lab-tested, COA-verified peptides with optional physician oversight. Sourced from US-regulated facilities.

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