Hexarelin
Also known as: Examorelin
Potent hexapeptide ghrelin mimetic with strong GH-releasing effects and cardioprotective properties.
Benefits
6
Conditions
5
Evidence
Clinical trials, preclinical cardioprotection research+ studies
Source
Synthetic hexapeptide ghrelin mimetic
Gabriel Brain Score
Moderate
Overview
Potent hexapeptide ghrelin mimetic with strong GH-releasing effects and cardioprotective properties.
Mechanism of Action
Binds GHS-R1a ghrelin receptor with high affinity, produces large GH pulses (greater than GHRP-6), also binds CD36 receptor for cardioprotection independent of GH, may desensitize with chronic use.
Key Benefits
- ✓Very potent GH release
- ✓Cardioprotective effects
- ✓Increased muscle mass
- ✓Enhanced recovery
- ✓Improved bone density
- ✓Neuroprotection
Clinical Applications
Dosing Guidelines
Subcutaneous injection
* Dosing should be individualized. Always consult with a qualified healthcare practitioner.
Research & Evidence
Clinical trials, preclinical cardioprotection research
Clinical trials demonstrate potent GH release. Unique cardioprotective effects via CD36 shown in preclinical models. Desensitization limits long-term continuous use.
Safety Information
Potential Side Effects
- •Increased hunger
- •Water retention
- •Cortisol elevation (mild)
- •Desensitization with prolonged use
Contraindications
- Active cancer
- Pregnancy
- Breastfeeding
Interactions
- ⚠Synergistic with GHRH analogs
Quick Facts
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