Growth HormoneModerate Evidence

GHRP-2

Also known as: Growth Hormone Releasing Peptide-2

Synthetic ghrelin mimetic that stimulates GH release with moderate appetite stimulation.

Benefits

Conditions

Evidence

Clinical trials, preclinical research+ studies

Source

Synthetic hexapeptide ghrelin mimetic

Gabriel Brain Score

Moderate

Overview

Synthetic ghrelin mimetic that stimulates GH release with moderate appetite stimulation.

Mechanism of Action

Binds ghrelin receptor (GHS-R1a) to trigger GH release, moderate cortisol and prolactin elevation, increases appetite via ghrelin pathway, synergistic with GHRH analogs for maximal GH pulse.

Key Benefits

✓Strong GH pulse induction
✓Increases IGF-1
✓Enhanced muscle growth
✓Improved recovery
✓Better sleep quality
✓Appetite stimulation (beneficial for some)

Clinical Applications

Growth hormone deficiencyMuscle wastingPoor appetiteRecovery from injuryAge-related GH decline

Dosing Guidelines

Subcutaneous injection

Typical Dose100-300 mcg

Frequency1-3 times daily

Duration8-12 weeks

* Dosing should be individualized. Always consult with a qualified healthcare practitioner.

Research & Evidence

Evidence Level

Moderate

Studies

Clinical trials, preclinical research

Summary

Clinical evidence for GH stimulation. Less selective than ipamorelin (affects cortisol/prolactin). Effective for GH elevation when combined with GHRH analogs.

Safety Information

Potential Side Effects

•Increased hunger
•Water retention
•Numbness/tingling
•Mild cortisol elevation

Contraindications

Active cancer
Pregnancy
Breastfeeding

Interactions

⚠Synergistic with CJC-1295 or GHRH

Quick Facts

CategoryGrowth Hormone

SourceSynthetic hexapeptide ghrelin mimetic

Legal StatusResearch compound, not FDA approved

Gabriel Brain Score

78/ 100

Source Your Protocol

Our preferred peptide partner offers lab-tested, COA-verified peptides with optional physician oversight. Sourced from US-regulated facilities.

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