GHRP-2
Also known as: Growth Hormone Releasing Peptide-2
Synthetic ghrelin mimetic that stimulates GH release with moderate appetite stimulation.
Benefits
6
Conditions
5
Evidence
Clinical trials, preclinical research+ studies
Source
Synthetic hexapeptide ghrelin mimetic
Gabriel Brain Score
Moderate
Overview
Synthetic ghrelin mimetic that stimulates GH release with moderate appetite stimulation.
Mechanism of Action
Binds ghrelin receptor (GHS-R1a) to trigger GH release, moderate cortisol and prolactin elevation, increases appetite via ghrelin pathway, synergistic with GHRH analogs for maximal GH pulse.
Key Benefits
- ✓Strong GH pulse induction
- ✓Increases IGF-1
- ✓Enhanced muscle growth
- ✓Improved recovery
- ✓Better sleep quality
- ✓Appetite stimulation (beneficial for some)
Clinical Applications
Dosing Guidelines
Subcutaneous injection
* Dosing should be individualized. Always consult with a qualified healthcare practitioner.
Research & Evidence
Clinical trials, preclinical research
Clinical evidence for GH stimulation. Less selective than ipamorelin (affects cortisol/prolactin). Effective for GH elevation when combined with GHRH analogs.
Safety Information
Potential Side Effects
- •Increased hunger
- •Water retention
- •Numbness/tingling
- •Mild cortisol elevation
Contraindications
- Active cancer
- Pregnancy
- Breastfeeding
Interactions
- ⚠Synergistic with CJC-1295 or GHRH
Quick Facts
Related Peptides
Tesamorelin
Synthetic GHRH analog FDA-approved for reducing visceral adipose tissue in HIV-associated lipodystrophy.
Hexarelin
Potent hexapeptide ghrelin mimetic with strong GH-releasing effects and cardioprotective properties.
CJC-1295
Long-acting GHRH analog that stimulates sustained growth hormone release.