Humanin
Also known as: HN, Mitochondrial-derived peptide
Mitochondrially-encoded peptide with cytoprotective and anti-aging properties.
Benefits
6
Conditions
6
Evidence
Preclinical animal and cell culture studies+ studies
Source
Mitochondrially-encoded peptide
Gabriel Brain Score
Strong
Overview
Mitochondrially-encoded peptide with cytoprotective and anti-aging properties.
Mechanism of Action
Protects against apoptosis via multiple pathways, enhances insulin sensitivity, reduces oxidative stress, protects neurons from β-amyloid toxicity, modulates mitochondrial function and cellular stress responses.
Key Benefits
- ✓Neuroprotection against Alzheimer's pathology
- ✓Enhances insulin sensitivity
- ✓Anti-apoptotic effects
- ✓Cardiovascular protection
- ✓Longevity promotion
- ✓Reduces oxidative stress
Clinical Applications
Dosing Guidelines
Subcutaneous injection
* Dosing should be individualized. Always consult with a qualified healthcare practitioner.
Research & Evidence
Preclinical animal and cell culture studies
Strong preclinical evidence for neuroprotection and metabolic benefits. No human clinical trials. Promising target for age-related disease interventions.
Safety Information
Potential Side Effects
- •Unknown in humans
Contraindications
- Pregnancy
- Breastfeeding
Interactions
- ⚠Unknown