Kisspeptin
Also known as: Metastin, KISS1
Neuropeptide that regulates gonadotropin-releasing hormone and reproductive function.
Benefits
6
Conditions
6
Evidence
Clinical trials in fertility and hypogonadism+ studies
Source
Synthetic kisspeptin analog
Gabriel Brain Score
Moderate
Overview
Neuropeptide that regulates gonadotropin-releasing hormone and reproductive function.
Mechanism of Action
Binds GPR54 receptor in hypothalamus, stimulates GnRH release, regulates LH and FSH secretion, controls onset of puberty and reproductive function, modulates sexual and emotional brain processing.
Key Benefits
- ✓Reproductive hormone regulation
- ✓Fertility enhancement
- ✓Libido support
- ✓Ovulation induction
- ✓Testosterone regulation
- ✓Sexual behavior modulation
Clinical Applications
Dosing Guidelines
Subcutaneous injection
* Dosing should be individualized. Always consult with a qualified healthcare practitioner.
Research & Evidence
Clinical trials in fertility and hypogonadism
Promising clinical trials for ovulation induction and hypogonadism. Mechanism well-characterized. Clinical applications under active investigation.
Safety Information
Potential Side Effects
- •Injection site reactions
- •Hot flashes
- •Headache
- •Nausea
Contraindications
- Pregnancy
- Hormone-sensitive cancers
Interactions
- ⚠Interacts with hormonal medications
Quick Facts
Related Peptides
Angiotensin 1-7
Protective peptide of the renin-angiotensin system with vasodilatory and anti-inflammatory effects.
Oxytocin
Neuropeptide hormone regulating social bonding, trust, reproduction, and stress modulation.
Vasopressin
Neuropeptide hormone regulating water balance, blood pressure, and cognitive function.