NeuroprotectiveModerate Evidence

Selank

Also known as: Tuftsin analogue

Russian anxiolytic and nootropic peptide derived from tuftsin with GABAergic and immunomodulatory effects.

Benefits

Conditions

Evidence

Russian clinical trials, preclinical studies+ studies

Source

Synthetic tuftsin analogue

Gabriel Brain Score

Strong

Overview

Russian anxiolytic and nootropic peptide derived from tuftsin with GABAergic and immunomodulatory effects.

Mechanism of Action

Enhances GABAergic activity for anxiety reduction, upregulates BDNF and modulates serotonin/dopamine systems, reduces pro-inflammatory cytokines via gene expression changes, immunomodulatory effects on immune cell function.

Key Benefits

✓Reduces anxiety and stress without dependency
✓Improves mood and emotional stability
✓Cognitive enhancement and focus
✓Anti-inflammatory effects
✓Immune system modulation
✓No sedation or withdrawal effects

Clinical Applications

Generalized anxiety disorderStress-related disordersDepression (mild to moderate)Cognitive impairmentImmune dysfunctionNeurasthenia

Dosing Guidelines

Intranasal drops

Typical Dose0.15% solution, 2-3 drops per nostril

Frequency2-3 times daily

Duration14-30 days cycles

* Dosing should be individualized. Always consult with a qualified healthcare practitioner.

Research & Evidence

Evidence Level

Moderate

Studies

Russian clinical trials, preclinical studies

Summary

Approved in Russia for anxiety and nootropic use. Extensive Russian literature with demonstrated efficacy. Limited Western clinical validation.

Safety Information

Potential Side Effects

•Nasal irritation
•Mild drowsiness
•Headache (rare)

Contraindications

Pregnancy
Breastfeeding

Interactions

⚠May potentiate benzodiazepines or other anxiolytics

Quick Facts

CategoryNeuroprotective

SourceSynthetic tuftsin analogue

Legal StatusApproved in Russia; research compound in most other countries

Gabriel Brain Score

86/ 100

Source Your Protocol

Our preferred peptide partner offers lab-tested, COA-verified peptides with optional physician oversight. Sourced from US-regulated facilities.

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