Parkinson's Integrative Support
An integrative protocol to support function and quality of life in Parkinson's disease alongside care from a neurologist.
52/100
Laurie Mischley, David Perlmutter
Ongoing, alongside neurological care
18 phases
1 condition
Protocol Overview
An integrative protocol to support function and quality of life in Parkinson's disease alongside care from a neurologist. Exercise has the strongest evidence; nutrition and supplements play a supporting role.
Safety Profile
Parkinson's involves loss of dopamine-making neurons, with mitochondrial stress, inflammation, alpha-synuclein misfolding and low glutathione all implicated. Exercise has the best evidence: vigorous, regular exercise improves movement and quality of life and may slow decline. Several supplements studied to slow progression, including high-dose CoQ10 (QE3 trial) and vitamin E (DATATOP trial), did not work in large trials, so supplements here support general health rather than slow the disease. Protein timing can matter for levodopa. Constipation and REM sleep behavior disorder often come years before diagnosis. An integrative approach works alongside medication, never instead of it.
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Book with GabrielAbout Evidence Score
The Evidence Score (0 to 100) rates the strength of evidence from studies in people for the uses listed: higher means stronger, more consistent research. It does not measure safety. It is not medical advice.
For education, not medical advice. Talk with a licensed clinician before you start, and never stop or change a prescribed medication without your prescriber.