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Hormonal

Melatonin

Circadian rhythm regulator; supports sleep onset, antioxidant, immune support, neuroprotective

Gabriel Score
85/ 100Excellent
CategoryHormonal
Applications7 conditions
FormsMelatonin (immediate-release or sustained-release)
How it works

Circadian rhythm regulator; supports sleep onset, antioxidant, immune support, neuroprotective

Typical Dosage

0.3-10mg/day (30-60 min before bed; start low)

Used for
InsomniaJet lagShift workDelayed sleep phaseImmune supportMigrainesAging

Practical Guide

Available Forms

Melatonin (immediate-release or sustained-release)

Natural Food Sources

  • Cherries
  • Walnuts
  • Tomatoes
  • Grapes (trace amounts)

Dosing should be individualized. Consult a qualified healthcare practitioner.

The Science

Evidence Base

Excellent85/100

Sleep hormone; lower doses (0.3-1mg) often more effective; sustained-release for maintenance; antioxidant; immune support; timing critical

Works Well With

MagnesiumL-theanineGABA5-HTPGlycine

Safety Profile

Interactions
  • May potentiate sedatives, blood thinners
  • May affect blood sugar, blood pressure
Contraindications
  • Autoimmune disease (may stimulate immunity)
  • Pregnancy
  • Depression (may worsen in some)

Trusted Brands

ThornePure EncapsulationsLife ExtensionNOWNatrol

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CategoryHormonal
Applications7
Gabriel Score85/100

Educational purposes only. Consult a qualified healthcare provider before starting any supplement protocol.

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