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Hormonal

I3C (Indole-3-Carbinol)

Estrogen modulator; converts to DIM in stomach; supports healthy estrogen metabolism and cell cycle regulation

Gabriel Score
78/ 100Good
CategoryHormonal
Applications5 conditions
FormsIndole-3-carbinol
How it works

Estrogen modulator; converts to DIM in stomach; supports healthy estrogen metabolism and cell cycle regulation

Typical Dosage

200-400mg/day

Used for
Estrogen dominanceBreast cancer preventionCervical dysplasiaPCOSFibrocystic breasts

Practical Guide

Available Forms

Indole-3-carbinol

Natural Food Sources

  • •Cruciferous vegetables (broccoli, Brussels sprouts, cabbage)

Dosing should be individualized. Consult a qualified healthcare practitioner.

The Science

Evidence Base

Good78/100

Precursor to DIM; found in cruciferous vegetables; supports healthy estrogen balance

Works Well With

DIM (metabolite)Calcium D-glucarateSulforaphane

Safety Profile

Interactions
  • May interact with estrogen therapies
  • Alters estrogen metabolism
Contraindications
  • Pregnancy
  • Breastfeeding
  • Hormone-sensitive cancers (monitor)

Trusted Brands

Pure EncapsulationsThorneLife ExtensionNOW

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CategoryHormonal
Applications5
Gabriel Score78/100

Educational purposes only. Consult a qualified healthcare provider before starting any supplement protocol.

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