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Herbs
Ashwagandha (Withania somnifera)
Adaptogen; reduces cortisol, modulates GABA, supports thyroid, neuroprotective via withanolides
Gabriel Score
88/ 100Excellent
CategoryHerbs
Applications6 conditions
FormsKSM-66 (full-spectrum root), Sensoril® (root+leaf), withanolide standardized extracts
How it works
Adaptogen; reduces cortisol, modulates GABA, supports thyroid, neuroprotective via withanolides
Typical Dosage
300-600mg/day (KSM-66 or Sensoril®)
Used for
AnxietyStressInsomniaFatigueLow testosteroneCognitive decline
Practical Guide
Available Forms
KSM-66 (full-spectrum root), Sensoril® (root+leaf), withanolide standardized extracts
Natural Food Sources
- •Root traditionally used in Ayurveda (not a food)
Dosing should be individualized. Consult a qualified healthcare practitioner.
The Science
Evidence Base
Excellent88/100
KSM-66 most studied; reduces cortisol significantly; may increase testosterone; avoid in hyperthyroidism; rare liver injury: stop if dark urine or yellow eyes
Works Well With
RhodiolaMagnesiumL-theanineZinc
Safety Profile
Interactions
- May potentiate sedatives, thyroid meds, immunosuppressants
Contraindications
- Pregnancy
- Breastfeeding
- Liver disease
- Hyperthyroidism
- Thyroid or autoimmune disease unless the prescriber agrees (recheck TSH in 6-8 weeks)
- Hormone-sensitive prostate cancer
Trusted Brands
JarrowThornePure EncapsulationsGaia Herbs
Build Your Protocol
Work with a practitioner to design a personalized supplement protocol.
Find a PractitionerCategoryHerbs
Applications6
Gabriel Score88/100
Educational purposes only. Consult a qualified healthcare provider before starting any supplement protocol.