Longevity

Fisetin

Senolytic (clears senescent cells), neuroprotective, anti-inflammatory, supports brain health and longevity

Gabriel Score

78/ 100Good

CategoryLongevity

Applications5 conditions

FormsFisetin (poor absorption—take with fat/oil)

How it works

Senolytic (clears senescent cells), neuroprotective, anti-inflammatory, supports brain health and longevity

Typical Dosage

100-500mg/day (high-dose pulses 1000-2000mg monthly)

Used for

AgingCognitive declineNeurodegenerative diseaseInflammationSenescent cell clearance

Practical Guide

Available Forms

Fisetin (poor absorption—take with fat/oil)

Natural Food Sources

•Strawberries
•Apples
•Persimmons
•Onions

Dosing should be individualized. Consult a qualified healthcare practitioner.

The Science

Evidence Base

Good78/100

Most potent senolytic flavonoid; clears "zombie cells"; neuroprotective; poor bioavailability (take with fat, or pulse high-dose monthly)

Works Well With

Quercetin (synergistic senolytic)NMN/NRResveratrolCurcumin

Safety Profile

Interactions

May interact with anticoagulants

Contraindications

None at therapeutic doses

Trusted Brands

Life ExtensionDoctor's BestSwansonNOW

Build Your Protocol

Work with a practitioner to design a personalized supplement protocol.

Find a Practitioner

CategoryLongevity

Applications5

Gabriel Score78/100

Educational purposes only. Consult a qualified healthcare provider before starting any supplement protocol.

Related Supplements

View all →

CoQ10/Ubiquinol

Mitochondrial electron transport chain cofactor; antioxidant; essential for ATP production; supports heart, brain, energy

Longevity

Quercetin

Senolytic (clears senescent cells), antioxidant, anti-inflammatory, antiviral, supports mitochondria

Longevity

Resveratrol

Polyphenol activating sirtuins (SIRT1); antioxidant, anti-inflammatory, cardioprotective, mimics caloric restriction

Longevity

Ready to explore natural options?

Connect with a Gabriel practitioner who specializes in evidence-based natural protocols.

Fisetin

Practical Guide

Available Forms

Natural Food Sources

The Science

Evidence Base

Works Well With

Safety Profile

Trusted Brands

Have questions about Fisetin?

Build Your Protocol

Related Supplements

CoQ10/Ubiquinol

Quercetin

Resveratrol

Ready to explore natural options?

Fisetin

Practical Guide

Available Forms

Natural Food Sources

The Science

Evidence Base

Works Well With

Safety Profile

Trusted Brands

Have questions about Fisetin?

Build Your Protocol

Related Supplements

CoQ10/Ubiquinol

Quercetin

Resveratrol

Ready to explore natural options?