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Longevity
Fisetin
Senolytic (clears senescent cells), neuroprotective, anti-inflammatory, supports brain health and longevity
Gabriel Score
78/ 100Good
CategoryLongevity
Applications5 conditions
FormsFisetin (poor absorption—take with fat/oil)
How it works
Senolytic (clears senescent cells), neuroprotective, anti-inflammatory, supports brain health and longevity
Typical Dosage
100-500mg/day (high-dose pulses 1000-2000mg monthly)
Used for
AgingCognitive declineNeurodegenerative diseaseInflammationSenescent cell clearance
Practical Guide
Available Forms
Fisetin (poor absorption—take with fat/oil)
Natural Food Sources
- •Strawberries
- •Apples
- •Persimmons
- •Onions
Dosing should be individualized. Consult a qualified healthcare practitioner.
The Science
Evidence Base
Good78/100
Most potent senolytic flavonoid; clears "zombie cells"; neuroprotective; poor bioavailability (take with fat, or pulse high-dose monthly)
Works Well With
Quercetin (synergistic senolytic)NMN/NRResveratrolCurcumin
Safety Profile
Interactions
- May interact with anticoagulants
Contraindications
- None at therapeutic doses
Trusted Brands
Life ExtensionDoctor's BestSwansonNOW
Build Your Protocol
Work with a practitioner to design a personalized supplement protocol.
Find a PractitionerCategoryLongevity
Applications5
Gabriel Score78/100
Educational purposes only. Consult a qualified healthcare provider before starting any supplement protocol.