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Longevity
Resveratrol
Polyphenol activating sirtuins (SIRT1); antioxidant, anti-inflammatory, cardioprotective, mimics caloric restriction
Gabriel Score
82/ 100Excellent
CategoryLongevity
Applications5 conditions
FormsTrans-resveratrol (active isomer), micronized or liposomal for absorption
How it works
Polyphenol activating sirtuins (SIRT1); antioxidant, anti-inflammatory, cardioprotective, mimics caloric restriction
Typical Dosage
150-500mg/day (trans-resveratrol)
Used for
Cardiovascular diseaseAgingCognitive declineCancer preventionMetabolic syndrome
Practical Guide
Available Forms
Trans-resveratrol (active isomer), micronized or liposomal for absorption
Natural Food Sources
- •Red wine
- •Grapes (skins)
- •Berries
- •Peanuts
Dosing should be individualized. Consult a qualified healthcare practitioner.
The Science
Evidence Base
Excellent82/100
"Red wine compound"; sirtuin activator; poor bioavailability (use micronized or liposomal); synergistic with NAD+ precursors
Works Well With
NMN/NR (synergistic NAD+ boost)QuercetinPterostilbeneCurcumin
Safety Profile
Interactions
- May increase bleeding risk
- May interact with anticoagulants
- Inhibits CYP3A4
Contraindications
- Bleeding disorders
- Surgery (discontinue 2 weeks prior)
Trusted Brands
ThornePure EncapsulationsLife ExtensionJarrow
Build Your Protocol
Work with a practitioner to design a personalized supplement protocol.
Find a PractitionerCategoryLongevity
Applications5
Gabriel Score82/100
Educational purposes only. Consult a qualified healthcare provider before starting any supplement protocol.