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Minerals
Magnesium L-Threonate
Crosses blood-brain barrier effectively; supports cognitive function, memory, neuroplasticity
Gabriel Score
78/ 100Good
CategoryMinerals
Applications5 conditions
FormsL-threonate (Magtein®)
How it works
Crosses blood-brain barrier effectively; supports cognitive function, memory, neuroplasticity
Typical Dosage
1500-2000mg/day (144-200mg elemental)
Used for
Cognitive declineMemory impairmentBrain fogADHDTraumatic brain injury
Practical Guide
Available Forms
L-threonate (Magtein®)
Natural Food Sources
- •Leafy greens
- •Spinach
- •Nuts
- •Seeds
- •Legumes
- •Whole grains
- •Fortified foods
- •Dairy
Dosing should be individualized. Consult a qualified healthcare practitioner.
The Science
Evidence Base
Good78/100
Only form clinically shown to cross BBB; higher cost; best for brain health specifically
Works Well With
Vitamin D3B-complexOmega-3
Safety Profile
Interactions
- Take apart from oral bisphosphonates such as alendronate
- Take apart from tetracycline and quinolone antibiotics (ask a pharmacist how far apart)
- Diuretics can raise or lower magnesium loss, depending on the type
- Long-term acid reflux drugs (PPIs) can lower magnesium
- Very high-dose zinc can lower magnesium absorption
Contraindications
- Kidney disease, unless a clinician advises it (extra magnesium can build up)
- More than 350 mg a day from supplements, the adult upper limit, unless a clinician advises it (diarrhea, nausea, cramping)
Trusted Brands
Life ExtensionJarrowNOW
Build Your Protocol
Work with a practitioner to design a personalized supplement protocol.
Find a PractitionerCategoryMinerals
Applications5
Gabriel Score78/100
Educational purposes only. Consult a qualified healthcare provider before starting any supplement protocol.