Black Cohosh
Actaea racemosa
Tradition of Use: Western, Native American
Mechanism of Action
Serotonergic activity, possible estrogen receptor modulation, anti-inflammatory
Key Conditions & Uses
Preparation
Tincture, capsule
Dosage
20-40mg extract 2x daily (standardized to triterpene glycosides)
Active Compounds
Triterpene glycosides, cimicifugoside, isoferulic acid
Interactions
May interact with hepatotoxic drugs; theoretically with hormone therapy
Contraindications
Liver disease; pregnancy; hormone-sensitive cancers (debated)
Evidence Level & Clinical Notes
Evidence Level:
Good - effective for menopause symptoms
Clinical Notes:
Mechanism unclear (not directly estrogenic); monitor liver function; takes 4-8 weeks
Traditional Chinese Medicine Context
Sheng Ma
Reduces hot flashes and night sweats during menopause
Conditions This Helps
Used In These Protocols
Quick Overview
Key Points
This information is for educational purposes. Always consult with a qualified healthcare provider before starting any herbal protocol or supplement regimen.
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