Kava
Piper methysticum
Tradition of Use: Western, Pacific Islander traditional
Mechanism of Action
Modulates GABA receptors, blocks sodium channels, anxiolytic without sedation
Key Conditions & Uses
Preparation
Tea, tincture, capsule
Dosage
70-250mg kavalactones daily
Active Compounds
Kavalactones (kavain, dihydrokavain, methysticin)
Interactions
Potentiates CNS depressants, alcohol; may interact with dopamine antagonists
Contraindications
Liver disease; pregnancy; Parkinson's disease; alcohol use
Evidence Level & Clinical Notes
Evidence Level:
Moderate - effective but hepatotoxicity concerns
Clinical Notes:
Hepatotoxicity reported with poor-quality extracts; traditional water extract safer
Conditions This Helps
Quick Overview
Key Points
This information is for educational purposes. Always consult with a qualified healthcare provider before starting any herbal protocol or supplement regimen.
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