Valerian
Valeriana officinalis
Tradition of Use: Western, European traditional
Mechanism of Action
Increases GABA availability, modulates GABA-A receptors, mild sedative effect
Key Conditions & Uses
Preparation
Tea, tincture, capsule
Dosage
300-600mg 30-60min before bed or 2-5ml tincture
Active Compounds
Valerenic acid, valepotriates, GABA
Interactions
Potentiates sedatives, alcohol, anesthetics; may interact with hepatotoxic drugs
Contraindications
Pregnancy; liver disease; surgery (discontinue 2 weeks prior)
Evidence Level & Clinical Notes
Evidence Level:
Good - effective for sleep latency
Clinical Notes:
May cause paradoxical stimulation in some; smell is strong and distinctive
Conditions This Helps
Used In These Protocols
Quick Overview
Key Points
This information is for educational purposes. Always consult with a qualified healthcare provider before starting any herbal protocol or supplement regimen.
Related Herbs from Western Herbalism
St. John's Wort
88Hypericum perforatum
Inhibits serotonin, dopamine, norepinephrine reuptake; modulates GABA and glutamate receptors
Milk Thistle
88Silybum marianum
Hepatoprotective via silymarin (antioxidant, anti-inflammatory, regenerates hepatocytes)
Ginger
87Zingiber officinale
Anti-inflammatory, antiemetic, warming circulatory stimulant, digestive, analgesic