Orthomolecular Psychiatry

High-dose vitamin therapy to correct biochemical imbalances underlying mental illness.

Evidence Score

71/100

Developer

Abram Hoffer, Linus Pauling

Duration

3-12 months to see full benefits, ongoing use

Steps

10 phases

Conditions

5 targeted

Protocol Overview

High-dose vitamin therapy to correct biochemical imbalances underlying mental illness. Emphasizes niacin (B3), vitamin C, B6, zinc, and essential fatty acids. Alternative to psychiatric medications or used adjunctively.

Conditions Treated

SchizophreniadepressionbipolaranxietyADHD

Schizophrenia →Anxiety & Depression →Bipolar Disorder →ADHD (Children & Adults) →

Key Resources

Journal of Orthomolecular Medicine, "Niacin: The Real Story" by Abram Hoffer, International Society for Orthomolecular Medicine (ISOM)

Supplements & Herbs

Copper

Safety Profile

Contraindications & Risks

High-dose niacin: Liver stress (monitor enzymes), flushing (can use flush-free but less effective), gout, ulcers

Important Notes

Hoffer treated 1000+ schizophrenia patients with 50-80% recovery rate (controversial). Niacin for schizophrenia has mixed trial results. High-dose vitamins generally safe. Pauling coined "orthomolecular." Growing acceptance for adjunctive use.

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EvidenceModerate

Evidence Score71/100

Categorymental health

Duration3-12 months to see full benefits, ongoing use

About Evidence Score

The Evidence Score rates the strength of clinical and scientific evidence behind this protocol. Higher scores indicate stronger research support. This is a research tool, not medical advice.

Educational purposes only. Some alternative protocols carry serious risks. Always consult qualified healthcare professionals before beginning any treatment.