Protocolstoxicity
toxicityLow

Cholestyramine (Mold Detox)

Cholestyramine is a prescription bile acid binder used off-label in Ritchie Shoemaker's protocol for chronic inflammatory response syndrome (CIRS) linked to mold.

Evidence Score

40/100

Developer

Ritchie Shoemaker

Duration

Usually several months, as set by your clinician

Steps

9 phases

Used for

3 conditions

Protocol Overview

Cholestyramine is a prescription bile acid binder used off-label in Ritchie Shoemaker's protocol for chronic inflammatory response syndrome (CIRS) linked to mold. It is thought to bind biotoxins in the gut so they leave the body. A licensed clinician decides whether it fits and the dose.

Used For

Mold illness (CIRS)mycotoxin exposurebile toxin elimination

Key Resources

Surviving Mold by Ritchie Shoemaker, CIRS-trained practitioners

Safety Profile

Contraindications & Risks
Complete bile duct obstruction, bowel obstruction
Severe constipation
Phenylketonuria (some forms contain phenylalanine)
Taking several medications (binding interactions); review with your prescriber
Pregnancy or breastfeeding: only with your clinician
Important Notes

Shoemaker described CIRS and its treatment sequence. Cholestyramine is FDA-approved for high cholesterol and some itching from bile problems; its use for mold illness is off-label and supported mainly by Shoemaker's own studies. CIRS is not widely accepted in mainstream medicine. Leaving the exposure comes first. Insurance may not cover testing.

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EvidenceLow
Evidence Score40/100
Categorytoxicity
DurationUsually several months, as set by your clinician

About Evidence Score

The Evidence Score (0 to 100) rates the strength of evidence from studies in people for the uses listed: higher means stronger, more consistent research. It does not measure safety. It is not medical advice.

For education, not medical advice. Talk with a licensed clinician before you start, and never stop or change a prescribed medication without your prescriber.