Protocolsautoimmune
autoimmuneModerate-High

Thyroid Optimization - Hashimoto's

Root-cause protocol for Hashimoto's addressing autoimmune triggers (gluten, infections, toxins, stress) alongside thyroid hormone optimization.

Evidence Score

85/100

Developer

Izabella Wentz, Datis Kharrazian

Duration

6-12 months to see antibody reduction, ongoing management

Steps

12 phases

Conditions

3 targeted

Protocol Overview

Root-cause protocol for Hashimoto's addressing autoimmune triggers (gluten, infections, toxins, stress) alongside thyroid hormone optimization. Goes beyond TSH suppression to reduce antibodies.

Conditions Treated

Hashimoto's thyroiditishypothyroidismautoimmune thyroid

Key Resources

Hashimoto's Protocol by Izabella Wentz, "Why Do I Still Have Thyroid Symptoms?" by Datis Kharrazian, functional medicine thyroid protocols

Supplements & Herbs

Safety Profile

Contraindications & Risks
Hyperthyroid phase during Hashimoto's flare (rare), over-replacement with thyroid hormone
Important Notes

Hashimoto's is autoimmune attack on thyroid - most common cause of hypothyroidism in developed countries. Standard care (levothyroxine only) misses the autoimmune component. Goal: reduce antibodies and stop progression. Gluten elimination is non-negotiable - molecular mimicry proven. Many need T3 in addition to T4 (poor conversion, high reverse T3). Selenium lowers TPO antibodies in RCTs. LDN is breakthrough for autoimmunity (immune modulation). Address root causes: gut permeability, infections, stress. Test don't guess. Iodine controversial - can flare Hashimoto's but deficiency also problematic (use selenium protection, start low). Optimal labs: Free T3 upper third of range, free T4 mid-range, TSH often suppressed on optimal dose (that's OK). Thyroid antibodies can normalize over time with protocol.

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EvidenceModerate-High
Evidence Score85/100
Categoryautoimmune
Duration6-12 months to see antibody reduction, ongoing management

About Evidence Score

The Evidence Score rates the strength of clinical and scientific evidence behind this protocol. Higher scores indicate stronger research support. This is a research tool, not medical advice.

Educational purposes only. Some alternative protocols carry serious risks. Always consult qualified healthcare professionals before beginning any treatment.