Protocolsautoimmune
autoimmuneModerate

Thyroid Optimization - Hashimoto's

A root-cause protocol for Hashimoto's that looks at possible triggers (gluten, nutrient gaps, gut health, infections, stress) alongside thyroid hormone managed by your clinician.

Evidence Score

62/100

Developer

Izabella Wentz, Datis Kharrazian

Duration

6 to 12 months to see antibody changes, then ongoing management

Steps

12 phases

Used for

3 conditions

Protocol Overview

A root-cause protocol for Hashimoto's that looks at possible triggers (gluten, nutrient gaps, gut health, infections, stress) alongside thyroid hormone managed by your clinician.

Used For

Hashimoto's thyroiditishypothyroidismautoimmune thyroid

Key Resources

Hashimoto's Protocol by Izabella Wentz, "Why Do I Still Have Thyroid Symptoms?" by Datis Kharrazian, functional medicine thyroid protocols

Supplements & Herbs

Safety Profile

Contraindications & Risks
A hyperthyroid phase during a flare, over-replacement with thyroid hormone (fast heart rate, anxiety, bone loss), selenium above 400 mcg a day (toxicity), high-dose iodine without a clinician, pregnancy (thyroid needs change quickly; work closely with your clinician)
Important Notes

Hashimoto's is an autoimmune attack on the thyroid and the most common cause of hypothyroidism in the US. Thyroid hormone replaces what the gland can't make; this protocol adds work on the immune side alongside it. Selenium has randomized trials showing lower TPO antibodies, though effects on symptoms are less clear. A gluten-free diet is worth a careful trial, and celiac testing comes first. Some people convert T4 to T3 poorly, and a clinician can review whether T3 belongs in their plan. LDN is used by some clinicians, but trials in Hashimoto's are limited. Test, don't guess: antibodies can fall over time for some people.

Find a Practitioner

Gabriel can find and book a practitioner who works with this approach.

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EvidenceModerate
Evidence Score62/100
Categoryautoimmune
Duration6 to 12 months to see antibody changes, then ongoing management

About Evidence Score

The Evidence Score (0 to 100) rates the strength of evidence from studies in people for the uses listed: higher means stronger, more consistent research. It does not measure safety. It is not medical advice.

For education, not medical advice. Talk with a licensed clinician before you start, and never stop or change a prescribed medication without your prescriber.