LongevityAvailable now

NAD+ IV Therapy

Recharge your cellular batteries

4.956 verified reviews
2-4 hours$250 - $750

20 practitioners are currently mapped for this treatment.

NAD+ IV Therapy
Visit PreviewLongevity

During the visit

Comprehensive health assessment and metabolic screening before your first infusion

Comfortable IV placement by an experienced nurse in a relaxing clinical environment

Slow infusion over 2-4 hours—NAD+ must be administered gradually to minimize flushing and nausea

Mild chest tightness, flushing, or cramping is normal and managed by adjusting drip rate

Duration

2-4 hours

Starting at

$250

Practitioner access

20 mapped

Category

Longevity

About this treatment

What this treatment is designed to do

Nicotinamide adenine dinucleotide (NAD+) is arguably the most important molecule you've never heard of. Present in every living cell, NAD+ is the essential coenzyme that powers mitochondrial energy production, activates sirtuins (the "longevity genes" that regulate DNA repair and cellular aging), and maintains the integrity of your genome. The problem: NAD+ levels decline by approximately 50% every 20 years of life, and this decline is now understood to be a primary driver of aging itself.

NAD+ IV therapy delivers this critical molecule directly into your bloodstream at concentrations impossible to achieve through oral supplementation. While oral NMN and NR precursors must survive digestion, conversion, and transport before reaching cells, intravenous NAD+ achieves immediate bioavailability and rapid tissue saturation. Patients typically report effects within the first session—enhanced mental clarity, improved energy, and a profound sense of cellular "awakening" that many describe as feeling years younger.

Beyond anti-aging, NAD+ IV therapy has shown remarkable promise in addiction recovery, where it helps restore neurotransmitter balance and reduce withdrawal symptoms. It's also being studied for neuroprotection in Alzheimer's and Parkinson's disease, chronic fatigue syndrome, and metabolic disorders. This is not a trendy drip bar add-on—it's foundational longevity medicine backed by Nobel Prize-winning biochemistry.

Visit flow

What happens during the session

1

Comprehensive health assessment and metabolic screening before your first infusion

2

Comfortable IV placement by an experienced nurse in a relaxing clinical environment

3

Slow infusion over 2-4 hours—NAD+ must be administered gradually to minimize flushing and nausea

4

Mild chest tightness, flushing, or cramping is normal and managed by adjusting drip rate

5

Many patients read, work, or rest during the extended infusion time

6

Post-infusion assessment and personalized protocol recommendations (most benefit from 3-6 session series)

Best for

Why people usually choose this

Adults over 35 experiencing age-related energy decline

Individuals committed to evidence-based longevity protocols

Those recovering from addiction or substance dependence

People with chronic fatigue, brain fog, or cognitive decline

Key outcomes

What people hope to improve

Restored cellular energy production and mitochondrial function

Activation of sirtuin longevity pathways and enhanced DNA repair

Improved mental clarity, focus, and cognitive performance

Support for addiction recovery and neurotransmitter rebalancing

Gabriel intelligence

How Gabriel makes this treatment more actionable

Treatment fit

Root-cause context before you book

Gabriel can help decide whether nad+ iv therapy fits your symptoms, labs, and recovery goals before you spend money on a session.

Protocol pairing

Connect sessions to a real plan

Gabriel can pair this with diagnostics, supplements, peptides, and follow-up cadence so it fits into a real protocol instead of sitting in isolation.

Practitioner match

Find the right clinic, not just the nearest one

Gabriel uses trust, treatment fit, and modality overlap to surface practitioners who are more likely to be a strong match for this exact treatment path.

Evidence & safety

What to know before committing

NAD+ biology earned a Nobel Prize in 1929 and has been the subject of over 10,000 published studies. Research from Harvard Medical School (Sinclair Lab), the National Institute on Aging, and institutions worldwide confirms the critical role of NAD+ decline in aging and disease. Clinical studies published in Nature Aging, Cell Metabolism, and Science demonstrate that NAD+ replenishment restores mitochondrial function, activates sirtuins, and reverses age-related cellular decline. IV administration is generally well-tolerated; common side effects include transient flushing, nausea, and chest tightness, which resolve with rate adjustment. Administered under medical supervision by trained IV therapy practitioners.

Top matches

Practitioners offering this treatment

Sorted by Gabriel Trust Score and treatment fit so the first click is closer to the right clinic, not just the loudest listing.

20 mapped practitioners
91
Leah M. Geoghegan, AGNP-C, IFMCPFunctional MedicineElite
5 · 34 reviews
Book
91
Truc Nguyen, MD, IFMCPMDElite
Alpharetta, Georgia
4.9 · 85 reviews
Book
90
Kimberly Shine, MDMDElite
Pasadena, California
4.8 · 143 reviews
Book
87
Susannah Kerwin, ANP-BC, HNP, IFMCPFunctional MedicineStrong
5 · 57 reviews
Book
87
Werner Vosloo, NDNDStrong
St. George, Utah
4.8 · 26 reviews
Book

Patient reviews

What patients say after treatment

Reviews are shown here as outcome context. They do not replace Gabriel’s fit analysis or practitioner trust scoring.

4.9

56 verified reviews

Jonathan W.

Verified

1 week ago

I'm 52 and after my first NAD+ IV, I felt like I was 35 again. The mental clarity was immediate—like someone cleaned a foggy windshield. By my third session, my energy levels were consistently higher than they'd been in a decade. This is the real deal for longevity.

Diana K.

Verified

3 weeks ago

I did a 6-session NAD+ protocol to support my recovery journey. The difference in my brain chemistry was remarkable—cravings diminished, anxiety decreased, and I felt a sense of mental balance I hadn't experienced in years. My recovery counselor noticed the change immediately.

Michael R.

Verified

1 month ago

Fair warning: the infusion takes a while and you may feel some flushing and chest tightness—but it's manageable and the nurse adjusted the drip rate whenever I felt uncomfortable. The results were worth every minute. My HRV scores improved measurably within a week.

Patricia L.

Verified

2 months ago

Excellent therapy but budget accordingly—this is premium medicine. After four sessions, my chronic fatigue has improved dramatically and my bloodwork shows improved metabolic markers. The clinic was professional and the nursing staff was top-notch. Planning to do quarterly maintenance sessions.

Not sure if this treatment is the right next move?

Tell Gabriel what you are dealing with and what you have already tried. You will get a more useful answer than a generic treatment directory can give.