Protocolsnutrition
nutritionModerate

Male Testosterone Optimization

A protocol to support healthy testosterone through sleep, training, diet and supplements, and to use testosterone therapy safely when a clinician confirms it is needed.

Evidence Score

68/100

Developer

Abraham Morgentaler, Jay Campbell, functional medicine

Duration

Natural optimization 3 to 6 months; testosterone therapy is ongoing with monitoring

Steps

10 phases

Used for

5 conditions

Protocol Overview

A protocol to support healthy testosterone through sleep, training, diet and supplements, and to use testosterone therapy safely when a clinician confirms it is needed.

Used For

Low testosteroneandropauseerectile dysfunctionlow libidofatigue

Key Resources

Testosterone for Life by Abraham Morgentaler, "Testosterone Optimization Therapy" by Jay Campbell, Endocrine Society testosterone therapy guideline

Supplements & Herbs

Safety Profile

Contraindications & Risks
Testosterone therapy: active or suspected prostate or breast cancer, high hematocrit, untreated severe sleep apnea, recent heart attack or stroke, and anyone trying to conceive. A clinician weighs each case. Ashwagandha: avoid with thyroid medication or autoimmune disease unless your clinician agrees
Important Notes

Testosterone tends to drift down with age, and obesity, poor sleep and some medicines lower it further. Symptoms include fatigue, low libido, erectile problems, low mood, muscle loss and fat gain. A total testosterone below about 300 ng/dL on repeat morning tests, with symptoms, is the usual threshold for therapy. Morgentaler's research changed thinking on prostate cancer risk, and the 2023 TRAVERSE trial found no increase in major heart events in men with low testosterone on therapy. Lifestyle steps, weight loss and treating sleep apnea can raise testosterone for many men. Therapy can help those who need it a great deal, with careful monitoring by a licensed clinician.

Find a Practitioner

Gabriel can find and book a practitioner who works with this approach.

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EvidenceModerate
Evidence Score68/100
Categorynutrition
DurationNatural optimization 3 to 6 months; testosterone therapy is ongoing with monitoring

About Evidence Score

The Evidence Score (0 to 100) rates the strength of evidence from studies in people for the uses listed: higher means stronger, more consistent research. It does not measure safety. It is not medical advice.

For education, not medical advice. Talk with a licensed clinician before you start, and never stop or change a prescribed medication without your prescriber.