Protocolsautoimmune
autoimmuneLow-Moderate

Autoimmune Flare Management Protocol

Short-term protocol to help calm autoimmune flares with an anti-inflammatory diet, gut support, rest and selected supplements, used alongside your rheumatologist's care.

Evidence Score

50/100

Developer

Various functional medicine, integrative rheumatology

Duration

1 to 3 weeks to calm a flare, with your rheumatologist's plan

Steps

26 phases

Used for

3 conditions

Protocol Overview

Short-term protocol to help calm autoimmune flares with an anti-inflammatory diet, gut support, rest and selected supplements, used alongside your rheumatologist's care. Used during flares of conditions such as RA, lupus and MS.

Used For

Autoimmune flareinflammatory flareacute exacerbation

Key Resources

Autoimmune protocol (AIP) resources, "The Wahls Protocol" by Terry Wahls, functional medicine protocols, rheumatology literature

Safety Profile

Contraindications & Risks
Fasting is not for people who are underweight, pregnant, have an eating disorder, or take diabetes medication or steroids without their clinician. High-dose omega-3, curcumin and ginger can add to blood thinners. NSAIDs can harm the stomach and kidneys. Steroids have real side effects, and only your prescriber changes or stops them. Immune-stimulating herbs such as echinacea may not suit autoimmune disease. Coordinate with your rheumatologist
Important Notes

Autoimmune flares are periods of higher inflammation, pain, fatigue and organ-specific symptoms. Common triggers include stress, infections, food triggers, overexertion, poor sleep and hormone changes. Acting early can shorten a flare. A short, strict elimination diet removes common inflammatory foods, followed by careful reintroduction to find your triggers. Short fasts and fasting-mimicking diets have early research for autoimmune inflammation. Omega-3 shifts the body toward less inflammatory signaling. Curcumin has arthritis trials showing pain relief similar to some NSAIDs, though it can cause stomach upset and interact with blood thinners. Boswellia has small arthritis trials. SPMs are a newer, less studied category. Gut support (glutamine, zinc carnosine, DGL) targets gut barrier problems that may feed inflammation. Low-dose naltrexone is used to reduce flares over the longer term, not for acute flares. Steroids are sometimes necessary for severe flares, and a short course can limit damage. Rest is part of the treatment: pushing through a flare can make it worse. Work with your rheumatologist for severe flares, and use flares to learn your triggers.

Find a Practitioner

Gabriel can find and book a practitioner who works with this approach.

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EvidenceLow-Moderate
Evidence Score50/100
Categoryautoimmune
Duration1 to 3 weeks to calm a flare, with your rheumatologist's plan

About Evidence Score

The Evidence Score (0 to 100) rates the strength of evidence from studies in people for the uses listed: higher means stronger, more consistent research. It does not measure safety. It is not medical advice.

For education, not medical advice. Talk with a licensed clinician before you start, and never stop or change a prescribed medication without your prescriber.